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Postdoctoral Scientist in Radiopharmaceutical Development – Radiochemist/Radiopharmacist in part-time (50%)

ID: 279924

Art des Jobs Vollzeit
Eingetragen am 18.06.2025
Einsatzort Heidelberg

Jobbeschreibung Your Tasks
- Development of novel small-molecule and peptide-based radioligands for diagnostic, therapeutic, and theranostic applications; this includes rational drug design based on structure-activity relationships, synthetic route development, and comprehensive chemical and radiochemical characterization
- Radiolabeling of compounds with a broad spectrum of medically relevant radionuclides, including alpha-emitters, beta-emitters, and gamma-emitters
- Optimization of labeling protocols and evaluation of complex stability, radiochemical purity, and shelf-life under physiological conditions
- Functional characterization of radiolabeled compounds using a variety of in vitro assays, including receptor binding, internalization kinetics, and cellular retention studies; these experiments will be conducted independently or in close cooperation with team members
- Integration of feedback from biological testing to guide structural modifications and improve efficacy, specificity, and pharmacological profile
- Preparation of high-quality scientific manuscripts for peer-reviewed journals, as well as writing and contributing to competitive grant proposals and third-party funding applications
- Co-supervision of graduate students, interns, and early-career researchers; support includes training in synthetic chemistry, lab safety, and experimental planning, as well as mentoring on data interpretation, presentation, and scientific communication
- Regular presentation of research results at internal group meetings, institutional seminars, and national and international scientific conferences
Qualifikationen Your Profile
- Applicants should have a master's degree and PhD in chemistry, biochemistry, medicinal chemistry, pharmaceutical sciences, or a closely related field. An academic or research focus on drug design, organic chemistry, inorganic chemistry, coordination/complexation chemistry, or radiopharmaceutical sciences is particularly advantageous.
- Prior experience in handling radionuclides, radiolabeling techniques, and radiopharmaceutical synthesis is highly desirable. However, motivated candidates without prior experience in this field but with a strong interest in radiochemistry are also encouraged to apply.
- Experience with cell culture, biological assays, and small animals is of significant advantage but not a prerequisite.
- Demonstrated ability to work effectively in interdisciplinary and multi-institutional teams is expected. A collaborative mindset, openness to scientific exchange, and a proactive attitude toward project development are essential in this dynamic research environment.
- Excellent written and verbal communication skills in English or German are required. Candidates should be capable of preparing scientific reports, manuscripts, and presentations, and engaging in professional discussions across disciplines.
Firma Deutsches Krebsforschungszentrum
69120 Heidelberg
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