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| Art des Jobs | Vollzeit | |
| Eingetragen am | 04.06.2025 | |
| Einsatzort | Biberach/Riss | |
| Jobbeschreibung | Tasks & responsibilities - In your new role, you will evaluate and implement advanced LC-MS approaches (e.g., micro-LC, column-switching, MS3, immune-capture) to achieve highly sensitive, targeted quantitation of biomarkers. - Furthermore, you will develop, validate, and implement targeted, quantitative, fit-for-purpose LC-MS assays biomarkers, with a focus on proteins. - You will plan and execute work to timely support clinical trials and translational studies, including sample handling and preparation, LC-MS analysis, data analysis, critical evaluation, and reporting. - Moreover, you will ensure proper operation, troubleshooting, and maintenance of LC-MS and laboratory equipment. - You will contribute to laboratory operation, organization and documentation according to our Quality system. - In addition, you will promote achievements through presentations and publications (internally and externally). - You will train and mentor less experienced staff. |
| Qualifikationen | Requirements
- PhD in analytical chemistry, biochemistry, pharmaceutical sciences, or a related discipline. - Proven hands-on experience in mass spectrometry (primarily: triple quadrupole; optionally: Orbitrap) and liquid chromatography techniques (RP-LC, HILIC, UHPLC), including sample preparation for proteins and peptides. - Demonstrated expertise and track record of developing MS-based quantitative assays in biological samples (especially biomarkers), ideally with pharmaceutical or CRO experience and knowledge of applicable guidelines. - Skilled in operating, troubleshooting, and maintaining LC-MS systems with a proven ability to independently lead complex bioanalytical projects and ensure high performance and data quality through a proactive and innovative mindset. - Strong understanding of protein quantitation techniques, including sample preparation strategies (like bottom-up proteomics, immunocapture), LC-MS (e.g. PRM, SRM-MS, MS3) as well as utilization of dedicated databases (e.g. UniProtKB, ExPASy, PeptideAtlas), software packages (e.g. Skyline). - Ability to work independently and team-oriented, with critical thinking, problem-solving attitude with attention to detail and strong organizational skills. - Proficient in English (spoken and written); German knowledge or willingness to learn is desirable |
| Firma |
Boehringer Ingelheim Pharma GmbH & Co. KG 88397 Biberach/Riss |
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