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Postdoctoral Position for Cancer Evolution m/w/d

ID: 279359

Art des Jobs Vollzeit
Eingetragen am 22.04.2025
Einsatzort Heidelberg

Jobbeschreibung Your Tasks
We are seeking an ambitious postdoctoral researcher to lead a team of technicians, masters, and graduate students to pioneer our next generation of discoveries. Experimental expertise in molecular and genome biology, computational fluency, and proven collaborative leadership are all absolutely required for this position. We have strong and long-standing alliances with the computational laboratories of Moritz Gerstung, Oliver Stegle, Angela Goncalves, and Jan Korbel, with whom joint appointments are common. Our laboratory’s philosophy is to hire the right person, and then together we shape a cutting-edge project to bridge the candidate’s interest and expertises with our current programs.

Our current research programs intersect large-scale genetic analysis utilizing experimental models, spatial biology, single-cell sequencing, tumorigenesis and mutagenesis. We have several running projects and new opportunities to delve into fundamental forces driving tumorigenesis, tumor evolution and spatial biology. We are investigating the principles of lesion segregation, see above, which is a mechanism underlying the acquisition and passage of somatic lesions throughout tumor progression. We also study sex-specific molecular differences within the acquisition and maintenance of malignancies, the identification and classification of cellular populations and niches and the development of both classical and AI/ML-based computational approaches to condense and interpret the full breadth of genetic and molecular changes associated with cancer inception.

We encourage applications from any scientifically qualified candidates, regardless of gender identity, disability, national origin, or any other demographic or personal factors.
Qualifikationen Your Profile
- A Ph.D. degree in molecular or cancer biology
- A strong background in experimental design and execution, along with associated computational competence (Please note: this specific job is not suitable for computational-only scientists)
- Strong track record in scientific communication, as evidenced by publication history
- Strong track record of collaborative work across discipline boundaries
- Proficiency in spoken and written English
- Evidence of collaborativity, creativity, and leadership

Knowledge within the following fields is a plus:
- Prior experience working in the field of molecular oncology
- Prior experience working with large-scale sequencing efforts
- (whole genome, whole transcriptome, methylation, single-cell sequencing)
- Prior experience working with spatial biology approaches, and early-adoption of cutting-edge technologies
- Prior experience working with Linux and high performance clusters (HPC)
- R/Python and Snakemake or Nextflow (or comparable platforms).
Firma Deutsches Krebsforschungszentrum
69120 Heidelberg
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